A prospective study was conducted to determine the frequency and clinical characteristics of childhood idiopathic hypercalciuria in children with primary hematuria. Study patients consisted of 93 children with recurrent gross hematuria. Study
patients
consisted of 93 children with recurrent gross hematuria or persisten microscopic hematuria of unknown etiology from July 1987 to December 1991.
@ES The following results were obtained.
@EN Out of 93 hematuric children. 26 (36%) were diagnosed as idiopathic hypercalciuria (24 hour urinary calcium excretion over 4mg/kg/day) and oral calcium loading test showed absorptive in 16 (0.13±0.13 of urinary Ca Cr ratio before oral
calcium
loading test 0.36±0.16 after test) and renal type in 10(0.35±0.12 before test. 0.41±0.09 after test). One child showed renal stone. Male to female ratio was 8:1 and family history of urinary stone was not observed. Hematuria was gross in 21
and
persistent microscopic in 5 cases. Serum Ca and phosphorus level were all within normal range 19.4±0.8, 4.9±1.0 mg/dl, respectively), and no significant difference was seen between the immunoactive parathyroid hormone level of absorptive type
and
that
of renal type (219.888.2 pg/ml, 271.7±226.2 pg/ml. Respectively). In summary, present study demonstrate that idiopathic hypercalciuria is a major cause of primary hematuria in Korean children, so that, in children with hematuria. Urinary calcium
excretion test should be done before renal biopsy.
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